Molecular Formula | C9H21NO4 |
Molar Mass | 207.27 |
Density | 1.005±0.06 g/cm3(Predicted) |
Boling Point | 85°C/0.1mmHg(lit.) |
Appearance | solid or viscous liquid |
pKa | 8.74±0.10(Predicted) |
Storage Condition | -20°C |
Sensitive | Sensitive to heat and air |
Refractive Index | 1.4440 to 1.4480 |
In vitro study | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
UN IDs | UN 2735 8/PG III |
Hazard Class | 8 |
Packing Group | III |
biological activity | m-PEG4-Amine is a PROTAC connection bridge and belongs to PEG class. m-PEG4-Amine can be used to synthesize a series of PROTAC molecules. m-PEG4-Amine is a degradable (cleavable) ADC connection bridge for the synthesis of antibody drug conjugates (ADCs). |
target | Cleavable PEGs |
in vitro study | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |